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Lancet Diabetes Endocrinol 2018;6:691-704.ArticlePubMed 41

If a patient had both obesity and type 2 diabetes, their GLP-1 prescription might still be covered under the diabetes diagnosis, though many plans implemented stricter documentation requirements to verify the primary treatment purpose

Disentangling these two categoriesfailed biology versus failed pharmacologyis essential to avoid repeating historical errors and to prioritize peptide systems with realistic translational potential