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While studying the effects of exendin-4 on the pancreas, Dr

Some of the most common or potential side effects include: Nausea Constipation Vomiting Diarrhea Abdominal Pain Headache Indigestion Injection Site Reactions Dizziness Back pain Increased Lipase or Amylase Altered Taste Nasopharyngitis (common cold) Passing Gas Bloating Belching Gastroenteritis Decreased Appetite Fatigue Gastroesophageal Reflux Disease Low Blood Sugar (hypoglycemia) in those with type II diabetes Upset Stomach These symptoms often subside as your body adjusts to the medications

The timeline for semaglutide to work depends partly on how quickly someone moves through these escalation phases, with most people reaching maintenance by week 17 at the earliest

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People switch between semaglutide and tirzepatide for several reasons: Weight loss expectations If someone isnt experiencing the weight loss they anticipated with one medication, they may switch to see if their body responds better to the other