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TZT, through modulation of the GLP-1 effect, may reduce Covid-19 associated glucose variability, inflammatory changes, and airway inflammation

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D., Clish, C

Microglial ferroptosis has been shown to induce neurotoxic astrocytes through pro-inflammatory signaling (such as IL-6 and TNF-), and ferroptosis-related genes including ACSL4 and GPX4 are highly enriched in microglia within HD lesions

GLP-1 receptors are expressed in brain regions involved in appetite and energy regulation, including the hypothalamus and brainstem