The primary risk of osteoporosis is fractures, especially for elderly osteoporosis where the mortality rate from fractures is extremely high, resulting in significant expenditure of public healthcare resources worldwide ( Glucagon-like peptide-1 (GLP-1) is one of the incretin hormones which are defined as intestinal hormones released in response to nutrient ingestion, which potentiate the glucose-induced insulin response
GLP-1 users are more open to discovery and trial, driven by cost sensitivity and the influence of retail media and social platforms
Indeed, eGFR values were greater in patients on tirzepatide compared to those on insulin glargine, with a mean eGFR decline rate of 1.4 ml/min/1.73 m 2 per year in tirzepatide users and a between-group difference in eGFR reduction of 2.2 ml/min/1.73 m 2 per year [49]
By Lana Pine | Published on June 19, 2025 4 min read People with diabetes who take glucagon-like peptide-1 (GLP-1) receptor agonists (such as Ozempic and Wegovy) may have more than twice the risk of developing a serious eye condition called neovascular age-related macular degeneration (nAMD) a leading cause of vision loss in older adults according to a large-scale study published in JAMA Ophthalmology
The changing face of diabetes in youth: lessons learned from studies of type 2 diabetes