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In patients with type 2 diabetes, treatment with semaglutide resulted in the following relative reductions in glucagon compared to placebo, fasting glucagon (8%), postprandial glucagon response (14 to 15%), and mean 24-hour glucagon concentration (12%)

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The glutathione system comprises the enzymes that synthesize glutathione within a cell as well as dedicated enzymes that use glutathione (GSH) as the means to exert antioxidant effects

doi: 10.1002/eji.200838318 88 ClambeyETMcNameeENWestrichJAGloverLECampbellELJedlickaPet al