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It significantly reduced colonic expression of iNOS and COX-2 while increasing the levels of endothelial nitric oxide synthase and peroxisome proliferator-activated receptor alpha, which are associated with vascular protection and anti-inflammatory responses

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However, some people may need lifelong treatment to keep their thyroid hormone levels in balance and prevent complications such as cardiovascular disease or osteoporosis

Heterologous expression of selenium-dependent glutathione peroxidase afford cellular resistance to paraquat