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doi: 10.1007/s00018-020-03574-z 49 de KoningTJ

The induction of two biosynthetic enzymes helps Escherichia coli sustain Heme synthesis and activate catalase during hydrogen peroxide stress

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Individuals with diabetes are already predisposed to vascular complications so introducing semaglutide to the mix could cause such an injury

Therefore, it is thought that HERC2 deficiency would result in a malfunctioning response to elevated iron levels, resulting in ferritinophagy, free iron release, and neuronal cell damage