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For the subgroup analysis of the time to the first occurrence of the main 5-component composite endpoint, the pre-specified Cox regression model also included an interaction between treatment group and the subgroup of interest, with the interaction P values evaluated using a score test

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Specific Populations Based on a population pharmacokinetic analysis, age, sex, race, and ethnicity, and renal impairment do not have a clinically meaningful effect on the pharmacokinetics of semaglutide

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