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However, it should be noted that the assembly of the PSII core proteins was considerably affected following the absence of the C-terminal processing of pD1, with the greatest effects observed in the subsequent assembly of PSII core proteins, especially for CP4 (Shi et al., 2021b, Shi et al., 2021a)

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All of which precede the definitive neural differentiation and underlying brain maturation and functionality [54, 55]