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Cardiac disorders: at the start of treatment, cases of congestive heart failure have occurred

up to 20% of adults face these, worsened by chronic stress activating the HPA axis via leaky gut

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doi: 10.1089/ars.2019.7905 224 WenkJSchllerJHinrichsCSyrovetsTAzoiteiNPoddaMet al

Among weight-loss pharmacotherapies, glucagon-like peptide-1 receptor agonists (GLP-1 RAs), including dual GLP-1 and glucose-dependent insulinotrophic polypeptide (GIP) receptor agonists, have demonstrated efficacy in patients with and without CKD, and are increasingly regarded as cornerstone therapies to improve outcomes in patients with multiple comorbidities