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In an open-label extension study, the long-term safety profile of DUPIXENT TCS in pediatric patients observed through Week 52 was consistent with that seen in adults with atopic dermatitis, with hand-foot-and-mouth disease and skin papilloma (incidence 2%) reported in patients 6 months to 5 years of age

Worsening diabetic retinopathy has been reported, necessitating caution for those with existing ocular conditions

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