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Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy

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Its unique ability to stimulate collagen synthesis, accelerate wound healing, and provide antioxidant protection creates comprehensive skin improvement that surpasses single-mechanism alternatives