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All fat depots are composed of adipocytes, resident innate and adaptive immune cells, represented mainly by macrophages, but also including neutrophils, dendritic cells, eosinophils, natural killer cells, innate lymphoid cells (ILCs), and B and T cells distributed in the stromal vascular fraction surrounded by a dense blood network (157)

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GSH imbalance and depletion are reported in many other brain disorders, including autism [28,29], bipolar disorder [30], schizophrenia [31], amyotrophic lateral sclerosis [32], and multiple sclerosis [33]

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These patients had all failed at least 1 year of standard treatment