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Risks include: Unknown ingredients that may interact with other medications or health conditions Lack of sterility, which can lead to infections Product that does not contain any active medication Taking GLP-1s can have side effects some moderate and some more serious, such as severe vomiting and diarrhea, severe constipation, gallstones, and pancreatitis

Check for step therapy requirements

Patients receive fresh medication on a predictable schedule, sidestep temperature-management anxiety, and never face the choice between discarding expired stock or risking subtherapeutic dosing

Peer review Peer review information Nature Communications thanks Christopher Reynolds and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

About the researchers The Italian endocrinologist and nutritionist Professor Paolo De Cristofaro has over 30 years of experience in treating eating disorders and obesity