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Pparalpha agonist-induced rodent tumors: Modes of action and human relevance

They might be cardiovascular medicine too

Here's a breakdown by injury type based on the published endpoints in animal models

Subsequently, repair or degeneration occur, which depend on multiple factors such as the type and extent of damage, the immune system, the genetic susceptibility to disc degeneration, which is linked with age, the biomechanical (functional) condition that is created by the injury, and finally the type of treatment: conservative (disc loading) or operative (disc unloading)