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Topical and systemic GLP-1R agonist administration both rescue retinal ganglion cells in hypertensive glaucoma

(68) reported positive immunoreactivity for GLP-1 receptors in PTC tissues, detected using a polyclonal anti-GLP-1 receptors antibody

GLP-1 plays an important role in glucose homeostasis and is secreted into the hepatic portal system in response to elevated glucose levels from food intake 10 , stimulating insulin synthesis and release from the pancreas 11

Some appetite changes, nothing dramatic

Susan Spratt, an endocrinologist and the senior medical director for the Population Health Management Office at Duke Health in North Carolina, questioned whether the increased risk was due to the rapid weight loss or some other mechanism of the drug