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Although it has a powerful physiological function, more studies have focused on its pathological role, mainly because it is involved in the pathogenesis of several neurodegenerative diseases, such as Parkinsons disease (PD) and dementia of Lewy body (DLB) [7, 8]

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MitoSOX Red dye (4 M) or PI (1 g/mL) were added together with Hoechst nuclear counterstain (1 g/mL) (Bio-Sciences) to the cells in DPBS Ca 2+ /Mg 2+ and incubated for 20 minutes at 37 C protected from light