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High-dose supplementation (400 mg/day) of riboflavin over a time course of three months was found to significantly reduce the frequency, duration and pain score of migraine attacks in both men and women in a meta-analysis of eight RCTs and one intervention study 66

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As the wealth of research continues to evolve, ongoing and future trials will help refine the role of GLP-1 RAs in a broader range of conditions and chart new therapies for the next generation of cardiovascular care