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Using doses below the therapeutic threshold may provide insufficient metabolic benefit, essentially exposing patients to medication risks without meaningful clinical gain

In a statement, it said the onus was on practitioners to do the right thing and follow good practice, including "only recommending treatments when there is an identified therapeutic need and a reasonable expectation of clinical efficacy and benefit"

Similar effects are found in semaglutide

In addition, post hoc sensitivity analyses were conducted to assess the robustness of the primary analyses

EPIC cohort: European Prospective Investigation into Cancer and Nutrition one of the largest dietary cohort studies, including ~400,000 adults across Europe, used to analyze alcohol and chronic disease relationships