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In type 2 diabetes, numerous clinical trials have shown that Semaglutide significantly reduces HbA1c levels, a measure of long-term blood sugar control, when compared to placebo or other antidiabetic medications
At 48 weeks on the highest dose (12 mg weekly) (Jastreboff et al., 2023): Nearly two-thirds of participants on the highest dose lost over 20% of their body weight
Volkow N
However, the studies on the effect of dietary Se and/or selenoprotein expression on, e.g., tight junction protein expression or systemic in vivo research on Se/selenoprotein in BBB and BCB permeability are currently absent, to the best of the authors knowledge
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