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By repeating the sequence of Glu-Pro-Ile-Tyr-Ala (EPIYA) motifs at the N-terminus of CagA, genes linked to cytotoxins enable the further classification of proteins into European and, North American type and East Asian-type CagA

Human biospecimens, clinical data and metabolite analysis of human samples Human biospecimens and deidentified clinical data were provided by the Wilmot Cancer Institute Biobank Shared Resource (BSR) at the University of Rochester

Copper and zinc are also required for SOD1 and SOD3 antioxidant enzymes, while mitochondrial SOD2 depends on manganese