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The ethanolic extract showed no mortality up to 2,000 mg/kg when administered orally (231)

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In comparison with healthy individuals, patients with COPD show significant differences in the airway microbiome, which is characterized by reduced microbial diversity, and the more severe the airflow limitation, the less diverse the microbial species in the sputum (64)

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Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, leading to a disruption of redox signaling and control and/or molecular damage (Sies, 2015) that harm lipids, proteins and DNA (Schieber and Chandel, 2014)