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In conclusion, the addition of semaglutide injections to lifestyle and metformin interventions can reduce BMI, waist and hip circumference, and body fat percentage, alleviate hyperandrogenemia, improve glucose metabolism and insulin resistance, and promote the restoration of normal menstrual cycles without exacerbating negative psychological emotions in individuals living with overweight/obesity and PCOS-related infertility

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When to stop or change semaglutide There is no regulator-provided vaginal-symptomspecific discontinuation threshold because these events are not established adverse reactions in product information

The precise rate of weight loss in the initial month can serve as a motivational factor for continued adherence to treatment and lifestyle changes, although its crucial to set realistic expectations and aim for a gradual and sustainable weight loss trajectory

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