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If you miss your scheduled dose entirely and remember within four days, take the missed dose as soon as possible, then resume your regular weekly schedule

Metabolism Based on an oral 14C-orlistat mass balance study in obese patients, two metabolites, M1 ((the hydrolyzed -lactone ring product of orlistat) and M3 (sequential metabolite after M1's cleavage of the N-formyl leucine side-chain), accounted for approximately 42% of total radioactivity in plasma

Common symptoms include persistent fatigue, pins and needles in the hands and feet, memory problems, and breathlessness