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Trabalhos utilizando tcnicas de transcriptmica demonstraram que o peptdeo pode modular genes envolvidos em processos como remodelao da matriz extracelular, resposta ao estresse oxidativo, organizao do tecido conjuntivo e manuteno da integridade cutnea
Alteration status and prognostic value of met in head and neck squamous cell carcinoma
Notably, these alterations occur prior to the onset of inflammation and induce the upregulation of epithelial-derived cytokines such as thymic stromal lymphopoietin (TSLP) and interleukin-33 (IL-33), which subsequently activate the Th2 immune axis in a sustained manner (Jo et al., 2018