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Group I (sitagliptin group) consisted of 23 adolescent participants with diabetic nephropathy and using the MiniMed 780G AHCL system, who received sitagliptin in a dose of 50 mg (Januvia 50 mg film-coated tablets, marketing authorisation holder Merck Sharp & Dohme and manufactured by Organ Pharma, UK) orally once daily with the main meal with their insulin pump therapy for 3 months [28, 29]

Overlapping androgenic suppression Isotretinoin reduces sebum production partly through retinoid-receptor-mediated downregulation of sebaceous-gland androgen signaling [12]

The original research focused on its role as a synthetic analog of the natural pineal peptide Epithalamin

doi: 10.1038/s41531-023-00603-z 47 RahimpourS.ZhangS.-C.VitekJ