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The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study

suggests that TB-500 may interact with cell movement as it binds globular actin (G-actin) and may modulate how actin filaments assemble to plausibly make endothelial cells more able to change shape, migrate, and form multicellular structures

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Convergent anti-fibrotic interest TB-500 and GHK-Cu have both been studied for organized matrix formation rather than disorganized scar tissue