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Baseline CVD risk among patients with T2DM also varied across the 4 SGLT2i CVOTs to date (Table 1)

Most of them are contraceptives (such as combined and progesterone-only contraceptive pills, ulipristal acetate and mifepristone), or GnRH antagonists (seven) reducing fibroid-related bleeding and anaemia, uterine volume and fibroid size

Four-year event rates were 7.8 % for obstructive and 7.7 % for extensive non-obstructive CADclosely approximating the 9.7 % rate in SELECTs control arm