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The results established semaglutide as the most effective anti-obesity medication studied to date, approaching weight loss magnitudes previously achievable only through bariatric surgery, and led to FDA approval of Wegovy for chronic weight management

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Obesity, 33(2), 267277

The Medicines and Healthcare products Regulatory Agency (MHRA) and the European Medicines Agency (EMA) have documented diarrhoea as a known adverse reaction in the product information for Rybelsus