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The cells were then incubated in the dark at 4 C for 30 min and washed twice with PBS

Beyond pregnancy, calorie restriction remains a key strategy for individuals with overweight or obesity, supporting improved insulin sensitivity and weight reduction

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The alteration of the brain microenvironment can result in impaired protective properties of the BBB and can lead to CNS diseases (16, 20)

also demonstrated the effect of Ubisol-Q 10 in blocking the neurodegenerative progression in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model by protecting the survival of dopaminergic cells with a robust astrocyte activation in the brain parenchyma, indicating the role of astroglia in this neuroprotection