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At 80 weeks of continuous treatment, participants on the highest 12 mg weekly dose achieved an average body weight reduction of 28.3% (equivalent to roughly 70 pounds per participant)

Human data show thyroid problems are rare, so routine testing is not standard unless there are specific symptoms, a palpable nodule, or other clinical concern

Documenting these alongside genetic predisposition data creates a comprehensive clinical narrative that helps insurers understand medical necessity beyond standard BMI or A1C thresholds alone

This timeline mismatch creates clinical confusion: once phentermine stops working or must be discontinued, you're left relying solely on semaglutidemaking the initial combination period unnecessary

If you have specific concerns regarding this matter, talk with your board-certified plastic surgeon about them to ensure optimal care