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Mastroberardino Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made

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Genomic DNA was isolated using buffer (100 mM Tris-HCl, 5 mM EDTA, 0.2% SDS, 200 mM NaCl + proteinase K) and precipitation with isopropanol