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The findings have not been replicated in larger or more diverse populations and should not be interpreted as proof that semaglutide extends lifespan or slows aging in the general population

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But a recent review of the literature by researchers at the University of Virginia raised a flag: they found that while GLP-1 drug therapy clearly reduces body weight and fat, these benefits dont translate into significant improvements in VO2max or overall cardiorespiratory fitness (2)

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