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The research concludes that for food manufacturers, restaurants and retailers, widespread GLP-1 adoption could lead to long-term shifts in demand, particularly for snack foods and fast food

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Trial design highlights Participants: Adults with BMI 30, or 27 with weight-related conditions Duration: 48 weeks Weekly injection Dose-ranging study (multiple escalating doses) Placebo comparison arm Headline results At the highest dose studied: Mean weight loss approached 24% at 48 weeks Many participants lost 20% Some individuals approached 25% reduction For context: Semaglutide: ~15% Tirzepatide: ~2022% Retatrutide (Phase 2): ~24% These results approach the lower range of bariatric surgical outcomes

Maintenance Phase (Weeks 5-12): Dosage: Reduce the dosage to 200mcg (2 sprays) of nasal spray TB-500 twice a day