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10.1016/j.tplants.2009.11.009 42 SzekelyG.AbrahamE.CseploA.RigoG.ZsigmondL.CsiszrJ.et al

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Tirzepatide increases heart rate modestly (average 24 bpm in clinical trials), while growth hormone effects on cardiac function require monitoring in susceptible individuals

Recently, certain senolytic and senostatic agents, such as rapamycin, Nrf2 activators, and calorie restriction, have demonstrated effectiveness in ameliorating cellular senescence

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