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Patients who could not tolerate Ozempic frequently cannot tolerate tirzepatide either

(2016) systematically analyzed colonic mucosal and fecal microbiota in 25 female patients with chronic constipation and 25 healthy controls, and demonstrated that colonic mucosal microbiota could distinguish constipated patients from healthy controls with 94% accuracy, independent of colonic transit time

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L-arginine is the precursor for the synthesis of nitric oxide (NO)