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Basically, it's your immune system saying, Hey, what's going on here?, and sending a bit of extra attention to the area

We note that these dose thresholds are intended as general reference ranges to promote consistent optimization of radiation dose and image quality, not as prescriptive limits that override clinical judgment

It may use different excipients, different concentrations, and different preservatives

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and Bacillus spp., resulting in an overall sterility failure