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Anti-Inflammatory and antioxidant effects of acetyl-L-carnitine on atherosclerotic rats

In temporal lobe epilepsy, levels of astrocytic glutamate transporters in hippocampus are reduced by up to 40%

Thus, adrenalectomized rats respond to intracerebroventricular (icv) leptin with a larger reduction in food intake and body weight than intact rats and the addition of glucocorticoids reduces leptins anorexigenic effects (Zakrzewska et al., 1997)

Cristae membrane dynamics - a paradigm change

In general, iron overload in cells, decreased GPX4 and xCT expression, activation of acylCoA synthetase long-chain family member-4 (ACSL4) and lysophosphatidylcholine acyltransferase-3, and an increase in lipid peroxidation are the four main mechanisms that induce ferroptosis [82,83,84]