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A diet with limited carbohydrates and saturated fat and enriched with high fiber and unsaturated fats, such as the Mediterranean diet, should be encouraged due to the cardiovascular benefits that are seen

A related study published in Nature Metabolism further supported these observations

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The initial gauge was set as 2 mm between the MN tips and the stainless-steel plate, with 10.00 N as the load cell capacity

Early coagonists showed improved glucose tolerance and lipid metabolism alongside weight loss driven by both reduced food intake and increased energy expenditure, such as cotadutide, a daily injectable, improves liver metabolism and has reduced HbA1c in clinical trials while also showing kidney-protective effects (e.g., reduced albumin-to-creatinine ratio)