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Furthermore, MDA can directly interact with DNA, causing strand breaks and base modifications, thereby adversely affecting sperm DNA integrity and reducing fertilization potential (115, 116)

Reactive oxygen species-sensitive fenofibrate-loaded dextran nanoparticles in alleviation of osteoarthritis

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Leveraging nuclear factor erythroid 2-related factor 2 (Nrf2) pathway Nrf2 is a ubiquitously expressed transcription factor that regulates the expression of around 20 antioxidant genes to provide protection against oxidative stress