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b Estimated using an ANCOVA based on data irrespectively of discontinuation of trial product or initiation of rescue medication adjusted for baseline value, background medication and region

Serum insulin-like growth factors and insulin-like growth factor-binding proteins: clinical implications

The two compounds work through entirely independent systems

GLP-1 medications are injectable, once daily or weekly, depending on the formulation

Conversely, the Reduction of Cardiovascular Events With Icosapent Ethyl-Intervention Trial (REDUCEIT), which included over 50% of participants with diabetes, demonstrated that daily supplementation with 4 g of icosapent ethyl (a highly purified and stable eicosapentaenoic acid ethyl ester) significantly reduced cardiovascular risk [336]