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Colton Jones, MD, the lead researcher and a hematology and medical oncology fellow at the University of Texas at San Antonio, and colleagues analyzed the health records of nearly 8,800 people with breast cancer and obesity taking both hormonal therapy and GLP-1s

Atta et al

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Quick answer: In head-to-head trials, tirzepatide (a dual GLP-1/GIP receptor agonist) produced greater weight loss than semaglutide (a single GLP-1 agonist) 20.2% vs 13.7% over 72 weeks in SURMOUNT-5 though semaglutides single-pathway selectivity keeps it valuable in research