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Figure 3 Understanding the detailed pathophysiology of RA is critical for developing targeted therapies to manage and potentially alter disease progression

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This intermittent approach can work when paired with strong lifestyle practices during off periods

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However, the brain is highly susceptible to oxidative damage due to its high oxygen consumption and limited antioxidant defenses (Sies et al., 2017)

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Heat can ease stiffness, whilst cold packs may reduce inflammation and swelling

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