Semaglutide The active ingredient in Wegovy and Ozempic The mean change in body weight from baseline to week 68 was -14.9% in the semaglutide group, as compared with -2.4% with placebo. STEP 1, Wilding JPH et al., NEJM 2021;384:989-1002 Tirzepatide The active ingredient in Mounjaro and Zepbound At 72 weeks, the mean percentage change in weight was -20.9% with 15 mg of tirzepatide, as compared with -3.1% with placebo. SURMOUNT-1, Jastreboff AM et al., NEJM 2022;387:205-216 These figures are trial averages for the branded formulations
Instead, discuss a dose reduction with your provider
If you win the appeal, the insurer will cover Zepbound
GLP-1 weight loss drugs explained Discover how medications like Mounjaro, Wegovy and Zepbound can help with weight loss and diabetes management
When to Contact Your GP About Taste Changes A sweet taste on its own is not usually an emergency, but there are situations where you should get medical advice