As documented by the FDA, practices such as taking a higher amount of the drug in a single dose, taking doses more frequently, or increasing the amount of the drug more quickly can cause serious gastrointestinal problems, including nausea, vomiting, diarrhea, and abdominal pain
Parasite Immunol (2020) 42(7):e12717
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Nitric Oxide 40:6774 Gokhale SV, Lele SS (2011) Dehydration of red beet root ( Beta vulgaris ) by hot air drying: Process optimization and mathematical modeling