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Tellier, M., Maudlin, I

Speer RE, Karuppagounder SS, Basso M, Sleiman SF, Kumar A, Brand D, Smirnova N, Gazaryan I, Khim SJ, Ratan RR (2013) Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by antioxidant metal chelators: from ferroptosis to stroke

However, genetic variation alone does not predict clinical response to supplementation

Gastrointestinal symptoms may be more easily managed in comparison to other physiological side effects through dietary intervention

For patients with persistent symptoms despite optimal thyroid hormone replacement, further investigation may be warranted to exclude other conditions such as coeliac disease , vitamin D deficiency, iron deficiency anaemia, or depression, all of which are more common in individuals with autoimmune thyroid disease