Serious but rare adverse effects include: Acute pancreatitis (patients should be advised to seek immediate medical attention for severe, persistent abdominal pain) Gallbladder disease, including cholecystitis and cholelithiasis Acute kidney injury, particularly in the context of dehydration from gastrointestinal side effects Hypoglycaemia, especially when used alongside other glucose-lowering medications Thyroid C-cell tumours (observed in rodent studies
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thus, it should be considered in patients with a history of ASCVD
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