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This results in the activation of mast cells and the release of inflammatory mediators, including histamine, leukotrienes, and others, which can manifest as pruritus, urticaria, angioedema, bronchospasm, vomiting, and hypotension

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Human Growth Hormone (HGH) In the United States, HGH is classified as a Schedule III controlled substance under the Anabolic Steroid Control Act , making it illegal to possess or distribute without a valid prescription