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Because it is a natural, biological extract, it contains a vast array of active neurotrophic factors, including BDNF (Brain-Derived Neurotrophic Factor), NGF, and remarkably high levels of GDNF-promoting elements

However, an excess of pro-angiogenic factors such as VEGF can trigger the production of pro-inflammatory cytokines and neuroinflammation, potentially contributing to neurodegeneration (McConnell et al

Together, the blend is hypothesized to offer enhanced therapeutic value in tissue repair models by acting through converging signaling pathways like FAK, eNOS, and VEGF 1-4

This can be a serious side effect

doi: 10.1111/j.1532-5415.2012.03998.x