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[DOI] [PubMed] [Google Scholar] 16.Mortazavi S.M., Moghimi H.R

(2019) Cystathione beta synthase deficiency and brain edema associated with methionine excess under betaine supplementation: Four new cases and a review of the evidence, JIMD reports, Vol

(2015) www.sciencedaily.com From the article: The epidemic of testosterone prescribing over the last decade has been primarily pushing testosterone as a tonic for sexual dysfunction and/or reduced energy in middle-aged men, neither of which are genuine testosterone deficiency states. [] Clearly, previous attempts to warn doctors and the public of this disease mongering that is potentially medically harmful and costly have not been effective

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However, they may have side effects, so they are usually prescribed only when other treatments are not effective